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jump to navigation menu 858 457 5873 contact us usa usa quick order add login cart (0) all cell culture cell lines prr ligands inhibitors antibodies vaccine adjuvants proteins & peptides cloning & expression vectors genes & promoters research fields products services about us distributors resources contact us careers meetings you are here home products cell culture selective antibiotics puromycin research fields products cell culture selective antibiotics blasticidin zeocin™ puromycin g418 (geneticin) hygromycin b gold phleomycin custom services puromycin puromycin (solution) unit size cat. code docs qty price selective antibiotic for the pac gene selective antibiotic for the pac gene selective antibiotic for the pac gene 100 mg (10 x 1 ml) 500 mg (50 x 1 ml) 500 mg (1 x 50 ml) ant-pr-1 ant-pr-5 ant-pr-5b msds tds msds tds msds tds + - + - + - $122.00 add to favorite $411.00 add to favorite $381.00 add to favorite about specifications contents details citations selection antibiotic: cell culture tested, sterile reagent puromycin is an aminonucleoside antibiotic produced by streptomyces alboniger . it specifically inhibits peptidyl transfer on both prokaryotic and eukaryotic ribosomes. this antibiotic inhibits the growth of gram positive bacteria and various animal and insect cells. puromycin can also be used in some particular conditions for the selection of e. coli transformants. resistance to puromycin is conferred by the pac gene encoding a puromycin n-acetyl-transferase [1]. animal cells are generally sensitive to concentrations from 1 to 10 µg/ml. 1. lacalle r. et al., 1989. molecular analysis of the pac gene encoding a puromycin n-acetyl transferase from streptomyces alboniger. gene. 79:375-80. -- back to the top specifications product concentration: 10 mg/ml cas number : 58-58-2 quality control: each lot is thoroughly tested to ensure the absence of lot-to-lot variation. purity: ≥ 98% (hplc) endotoxin level: < 5 eu/mg physicochemical characterization: ph, appearance cell-culture tested: potency validated in puromycin-sensitive and puromycin‑resistant mammalian cell lines non-cytotoxicity of trace contaminants: absence of long-term effects confirmed in puromycin-resistant cells back to the top contents puromycin dihydrochloride is supplied as a sterile filtered solution at 10 mg/ml in hepes buffer. this product is available in three pack sizes: ant-pr-1 : 10 x 1 ml (100 mg) ant-pr-5 : 50 x 1 ml (500 mg) ant-pr-5b : 1 x 50 ml (500 mg) puromycin is shipped at room temperature. upon receipt it should be stored at 4°c or -20°c. puromycin is a harmful compound. refer to safety data sheet for handling instructions. back to the top details formula: c 22 h 29 n 7 o 5 • 2hcl molecular weight: 544.3 structure : back to the top citations 2018 nat protoc. 13(1):155-169. live-cell measurements of kinase activity in single cells using translocation reporters. kudo t. et al. 2018 nat commun. 9(1):727. clonal dynamics towards the development of venetoclax resistance in chronic lymphocytic leukemia. herling cd. et al. 2017 nat commun. 8:15556. the pyrin domain-only protein pop2 inhibits inflammasome priming and activation. ratsimandresy ra. et al. 2017 sci rep. 7:41179. decreased expression of pseudogene ptenp1 promotes malignant behaviours and is associated with the poor survival of patients with hnscc. liu j. et al. 2017 nat commun. 8:15916. cdk4/6 and autophagy inhibitors synergistically induce senescence in rb positive cytoplasmic cyclin e negative cancers. vijayaraghavan s. et al. 2017 cell 169(2):203-215. mutation of the human circadian clock gene cry1 in familial delayed sleep phase disorder. patke a. et al. 2017 nat commun. 8:13998. contractile forces at tricellular contacts modulate epithelial organization and monolayer integrity. salomon j.et al. 2017 pnas 114(10):2675-2680. rational design of adjuvants targeting the c-type lectin mincle. decout a. et al. 2017 cell. 168(3):503-516.e12. pathogen-mediated inhibition of anorexia promotes host survival and transmission. rao s. et al. 2016 j immunol. 196(11):4522-35. novel teleost cd4-bearing cell populations provide insights into the evolutionary origins and primordial roles of cd4+ lymphocytes and cd4+ macrophages. takizawa f. et al. 2016 plos one. 11(1):e0146846. murine gprc6a mediates cellular responses to l-amino acids, but not osteocalcin variants. rueda p, harley e, lu y, stewart gd, fabb s, diepenhorst n, cremers b, rouillon mh, wehrle i, geant a, lamarche g, leach k, charman wn, christopoulos a, summers rj, sexton pm, langmead cj. 2016 nature. 35(7610):159-63. genetic dissection of flaviviridae host factors through genome-scale crispr screens. marceau cd. et al. 2016 nature 530(7588):108-12. an essential receptor for adeno-associated virus infection. pillay s, meyer nl, puschnik as, davulcu o, diep j, ishikawa y, jae lt, wosen je, nagamine cm, chapman ms, carette je. 2016 nat commun. 7:11807. myc/miz1-dependent gene repression inversely coordinates the circadian clock with cell cycle and proliferation. shostak a. et al. 2016 nucleic acids res. 44(10):4763-84. diverged composition and regulation of the trypanosoma brucei origin recognition complex that mediates dna replication initiation. marques ca. et al. 2016 nat commun. 7:12632. glycosylation and stabilization of programmed death ligand-1 suppresses t-cell activity. li cw. et al. 2015 cancer res. 75(7):1399-412. pdk1 and sgk3 contribute to the growth of braf-mutant melanomas and are potential therapeutic targets. scortegagna m, lau e, zhang t, feng y, sereduk c, yin h, de sk, meeth k, platt jt, langdon cg, halaban r, pellecchia m, davies ma, brown k, stern df, bosenberg m, ronai za. 2015 embo j. 34(9):1244-58. an lxr–ncoa5 gene regulatory complex directs inflammatory crosstalk-dependent repression of macrophage cholesterol efflux. gillespie ma, gold es, ramsey sa, podolsky i, aderem a, ranish ja. 2015 pnas 112(14):4298-303. phosphorylation of orf1p is required for l1 retrotransposition. cook pr, jones ce, furano av. 2015 sci signal. 8(376):ra44. phosphorylation of gata-6 is required for vascular smooth muscle cell differentiation after mtorc1 inhibition. xie y, jin y, merenick bl, ding m, fetalvero km, wagner rj, mai a, gleim s, tucker df, birnbaum mj, ballif ba, luciano ak, sessa wc, rzucidlo em, powell rj, hou l, zhao h, hwa j, yu j, martin ka. 2014 nucleic acids res. 42(2):1270-90 multiple myeloma-associated hdis3 mutations cause perturbations in cellular rna metabolism and suggest hdis3 pin domain as a potential drug target. tomecki r, drazkowska k, kucinski i, stodus k, szczesny rj, gruchota j, owczarek ep, kalisiak k, dziembowski a 2013 pnas 110(45):18150-5 reward-based hypertension control by a synthetic brain-dopamine interface. rössger k, charpin-el hamri g, fussenegger m 2012 pnas 109(23):9125-30 role of ccctc binding factor (ctcf) and cohesin in the generation of single-cell diversity of protocadherin-α gene expression. monahan k, rudnick nd, kehayova pd, pauli f, newberry km, myers rm, maniatis t 2012 nucleic acids res. 40(14):6725-40 targeted silencing of the oncogenic transcription factor sox2 in breast cancer. stolzenburg s, rots mg, beltran as, rivenbark ag, yuan x, qian h, strahl bd, blancafort p load more you may also need blasticidin selective antibiotic for the bsr, bls, or bsd genes pselect-puro expression plasmid with puromycin resistance gene plasmocin™ - mycoplasma elimination reagent mycoplasma elimination reagent customer service & technical support you must have javascript enabled to use this form. request type * request type technical support customer service other name * company email * city country phone * request content * research fields prrs & innate immunity vaccination autophagy cytokines cpg-free dna products cell culture cell lines prr ligands inhibitors antibodies vaccine adjuvants proteins & peptides cloning & expression vectors genes & promoters custom services immunom

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Domain Name: PUROMYCIN.COM
Registry Domain ID: 18825098_DOMAIN_COM-VRSN
Registrar WHOIS Server: whois.gandi.net
Registrar URL: http://www.gandi.net
Updated Date: 2017-01-19T08:29:37Z
Creation Date: 2000-02-01T09:13:14Z
Registry Expiry Date: 2022-02-01T09:13:14Z
Registrar: Gandi SAS
Registrar IANA ID: 81
Registrar Abuse Contact Email: abuse@support.gandi.net
Registrar Abuse Contact Phone: +33.170377661
Domain Status: clientTransferProhibited https://icann.org/epp#clientTransferProhibited
Name Server: A.DNS.GANDI.NET
Name Server: B.DNS.GANDI.NET
Name Server: C.DNS.GANDI.NET
DNSSEC: unsigned
URL of the ICANN Whois Inaccuracy Complaint Form: https://www.icann.org/wicf/
>>> Last update of whois database: 2017-11-25T00:41:32Z <<<

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The Registry database contains ONLY .COM, .NET, .EDU domains and
Registrars.

  REGISTRAR Gandi SAS

SERVERS

  SERVER com.whois-servers.net

  ARGS domain =puromycin.com

  PORT 43

  TYPE domain
RegrInfo
DOMAIN

  NAME puromycin.com

  CHANGED 2017-01-19

  CREATED 2000-02-01

STATUS
clientTransferProhibited https://icann.org/epp#clientTransferProhibited

NSERVER

  A.DNS.GANDI.NET 173.246.98.1

  B.DNS.GANDI.NET 213.167.229.1

  C.DNS.GANDI.NET 217.70.179.1

  REGISTERED yes

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